Urinary hormone metabolites testing provides a unique diagnostic view that no other hormone testing offers.  Because it assesses both parent hormones and their corresponding metabolites, it reveals how the body is breaking down key hormones like estrogens, progestogens, androgens, cortisol and melatonin.

This testing gives insight into whether we are fully detoxifying our hormones, which is important because some hormones can be carcinogenic if they don’t break down properly – leaving us more at risk for a variety of diseases, like cancer.

Why the Focus on Estrogen Metabolism?

A growing conversation in the medical community centers on estrogen metabolism and the risk for hormone-driven cancers. With every published study, there is increasing evidence that the amount of estrogen we make and how our bodies process (metabolize) this estrogen has significant implications for cancer risk. In women, this is breast cancer. In men, it’s prostate cancer.

Measuring hormone levels, as well as the resulting by-products (metabolites) is a simple, non-invasive way to better understand our risks.

When is it a good idea to consider urinary hormone metabolite testing? In cases where someone has:

  • Family history of hormone-dependent cancers – like breast or prostate
  • Normal saliva cortisol levels but still experiencing symptoms of fatigue
  • Symptoms of hormonal imbalance such as weight gain and insomnia
  • Symptoms of PCOS, such as acne and excess facial hair
  • Symptoms of menopause and ready to begin hormone replacement therapy
  • Symptoms of estrogen dominance while on physiological replacement dosages of therapy


Urine Hormone & Metabolite Testing also provides information about the impact that shifting hormone levels can have in men (andropause or male menopause) and women (perimenopause/menopause), producing symptoms such as:

  • Weight gain
  • Anxiety
  • Fatigue
  • Low sex drive and performance issues
  • Sleep disturbances
  • Mood instability
  • Brain fog
  • Hot flashes

Important Hormones that are Tested


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Hormones and Metabolites

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